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AKT, also known as protein kinase B (PKB) or Related to A and C kinases (RAC), is the cellular homolog of the viral oncogene v-AKT. It was originally cloned based on its homology to protein kinases A and C. AKT is activated in response to insulin, and various growth and survival factors. It is clear that AKT enzyme activity is both necessary and essential for cell survival, and AKT has been shown to be able to induce progression of the cell cycle as well as suppress apoptosis. The key role of AKT in the regulation of cell survival makes it a promising target for anti-oncogenic therapeutics.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| FACE™ AKT | 1 x 96 rxns | 48120 | $ 445 |  |
| FACE™ AKT | 5 x 96 rxns | 48620 | $ 1845 | |
| FACE™ AKT Chemi | 1 x 96 rxns | 48220 | $ 495 | |
| FACE™ AKT Chemi | 5 x 96 rxns | 48720 | $ 2050 | |
