YOUR CART
c-Jun is a component of the transcription factor AP-1, which binds and activates transcription at TRE/AP-1 elements. The c-Jun oncogene encodes a nuclear protein, p39, that interacts with the AP-1 c-Fos oncogene product and forms a transacting heterodimer. c-Jun plays an important role in the regulation of gene expression and signal transduction processes and is also suggested to be actively involved in the differentiation of B-chronic lymphocytic leukemia cells and Hodgkin’s Reed-Sternberg cells as well as in the malignant transformation of melanocytes, which makes it a promising drug target.
Contents & Storage
96-well plates for culturing cells, two primary antibodies (1 phospho-specific, 1 specific for native protein), HRP-conjugated secondary antibody, Quenching Solution, 1X Antibody Blocking Buffer, 1X Antibody Dilution Buffer, 10X PBS, 10% Triton X-100, 1% SDS Solution, Developing and Stop Solutions, and Crystal Violet Cell Quantification Solution. Storage conditions vary from room temperature to -20°C, see manual for details. All reagents are guaranteed stable for 6 months when stored properly.
