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c-Src (proto-oncogene tyrosine-protein kinase Src) is a 60 kDa tyrosine protein kinase that contains both SH2 and SH3 domains. c-Src is a lipid-modified signaling molecule (myristoylated) involved in cell-cell interactions, cell migration and proliferation through the phosphorylation of many substrates. c-Src is expressed at high levels in differentiated cells including neurons, platelets and macrophages, and can be activated by phospholipase D, insulin-like growth factor receptor, EGF-receptor, fibroblast growth factor receptor and prolactin receptor binding. c-Src can be phosphorylated on multiple sites to interact with polyoma virus middle T antigen, PYK2, HSP72 and caveolin, and efficient study methods are in high demand.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| FACE™ c-Src | 1 x 96 rxns | 48155 | $ 435 |  |
| FACE™ c-Src | 5 x 96 rxns | 48655 | $ 1825 | |
| FACE™ c-Src Chemi | 1 x 96 rxns | 48255 | $ 485 | |
| FACE™ c-Src Chemi | 5 x 96 rxns | 48755 | $ 2035 | |
