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Because cytochrome c plays a major role in apoptosis, its measurement can lead to greater understanding of certain diseases on a cellular level. Cytochrome c is an essential component of the mitochondrial respiratory chain. It is a soluble protein that is localized in the intermembrane space and loosely attached to the surface of the inner mitochondrial membrane. Cytochrome c is important to the process of creating cellular energy, the main function of mitochondria. When mitochondria are damaged, cytochrome c is released into the main body of the cell and, if the cell itself is damaged, into the surrounding tissue. The release of cytochrome c is part of the cascade of cellular events that leads to apoptosis, or programmed cell death. When the cycle that leads to apoptosis begins, cytochrome c appears outside the mitochondria within one hour.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| FunctionELISA™ Cytochrome c | 1 x 96 rxns | 48006 | $ 495 |  |
| FunctionELISA™ Cytochrome c | 5 x 96 rxns | 48506 | $ 2095 | |
