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The DNA Damage Assay is a simple, fast and accurate, 2-color fluorescent assay for the induction of double-stranded DNA (dsDNA) breaks. When cell cultures or animals are exposed to ionizing radiation or certain treatment compounds, double-stranded DNA breaks are created that rapidly result in the phosphorylation of the histone variant H2AX at serine 139. Because H2AX phosphorylation at serine 139 correlates very closely with each dsDNA break, phospho-H2AX is a sensitive marker for DNA damage and can be used to assess the effects and timing of DNA-damage inducing and DNA repair agents.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| DNA Damage Assay (Fluorescent) | 2 x 96 rxns | 18030 | $ 385 |  |
