YOUR CART
c-Myc is a transcription factor that regulates cell growth and differentiation, glycolysis and apoptosis. Deregulation of c-Myc has been implicated in the origin of diverse human cancers, and may contribute to as much as one-seventh of U.S. cancer deaths. Because of this link between c-Myc and cancer, accurate monitoring of c-Myc in cells, tissues and animals is crucial for many biomedical research and drug development projects. TransAM c-Myc Kits contain an antibody specific for the active form of c-Myc when bound to its target DNA. Because of c-Myc's regulation by MAPK, we also offer the TransAM MAPK Family Kit for studying the MAPK regulated transcription factors ATF-2, c-Jun, c-Myc, MEF2 and STAT1α.
Contents & Storage
One or five c-Myc 96-well plate(s) with plate sealer(s), primary antibody, HRP-conjugated secondary antibody, wild-type and mutated competitor oligonucleotides, positive control cell extract, DTT, Protease Inhibitor Cocktail, Lysis, Binding, 10X Washing and 10X Antibody Binding Buffers, and Developing and Stop Solutions. Reagent storage conditions vary from room temperature to -80°C, see manual for details. All reagents are guaranteed stable for 6 months when stored properly.
