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Elk-1 is a transcription factor that is activated by mitogen-activated protein kinases (MAPKs) and whose main function is the regulation of growth-related proteins in response to extracellular stimuli. Because of the importance of Elk-1 to the regulation of successful cell growth, accurate monitoring of Elk-1 in cells, tissues and animals is crucial for many biomedical research and drug development projects.
Figure 1: Monitoring Elk-1 activity in different cell lines with the TransAM Elk-1 Kit.
Different amounts of nuclear extracts from untreated U-937, untreated HeLa and HeLa (TPA, 10 min) cells are tested for Elk-1 activity using the TransAM Elk-1 Kit.
