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The Forkhead transcription factor FKHR (FOXO1) regulates expression of gluconeogenic factors and plays a key role in insulin regulation of glucose levels. Besides its role in glucose homeostasis, FKHR has been shown to be involved in pathological processes such as type 2 diabetes, cancer and organismal aging. The transcriptional output of FKHR is controlled by a two-tiered mechanism of phosphorylation and acetylation, and alterations in this balance can result in profound effects.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| TransAM™ FKHR (FOXO1) | 1 x 96 rxns | 46396 | $ 615 |  |
| TransAM™ FKHR (FOXO1) | 5 x 96 rxns | 46896 | $ 2615 | |
