The GATA family consists of six members, GATA 1-6, that bind to the (A/T)GATA(A/G) nucleotide motif. GATA family members are grouped into two subfamilies based on structural and expression comparisons. GATA-1, -2 and -3 are expressed predominantly in hematopoietic cells, and regulate differentiation and gene expression in T-lymphocytes, erythroids and megakaryocytes. GATA-4, -5 and -6 are found mainly in the heart and gut, and are involved in regulation of cardiogenesis and gut development. The TransAM GATA Family Kit measures GATA-1, -2 and –3, while TransAM GATA-4 is specific for studying GATA-4.
Contents & Storage
One, two or five GATA 96-well plates with plate sealers, GATA-1, -2 and -3 or GATA-4 primary antibodies, HRP-conjugated secondary antibody, GATA wild-type and mutated oligonucleotides, positive control cell extract, DTT, Protease Inhibitor Cocktail, Herring Sperm DNA, Lysis, Binding, 10X Washing and 10X Antibody Binding Buffer, and Developing and Stop Solutions. Reagent storage conditions vary from room temperature to -80°C, see manual for details. All reagents are guaranteed stable for 6 months when stored properly.

