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Hepatocyte Nuclear Factors (HNFs) are primarily required for cellular differentiation and metabolism. Unlike most transcription factor families, this group of evolutionarily conserved proteins does not have a common consensus-binding site. This makes assaying HNF family activity using classical EMSA or reporter assays cumbersome and time consuming. The TransAM HNF Family Kit contains multiple binding sites in each well, making it quick and easy to monitor HNF-1, -3α, -3β and -4α activity in a single assay. In addition, a TransAM HNF-1 Kit is available separately for researchers who want to monitor this important regulator of liver function.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| TransAM™ HNF Family | 2 x 96 rxns | 46296 | $ 995 |  |
| TransAM™ HNF-1 | 1 x 96 rxns | 46196 | $ 605 | |
| TransAM™ HNF-1 | 5 x 96 rxns | 46696 | $ 2595 | |
