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The transcription factor known as Nuclear Factor of Activated T cells (NFAT) binds to several sites within the regulatory region of the IL-2 gene and other genes induced during the immune response. Because its activation is inhibited by the main immunosuppressive drugs in current clinical use, cyclosporin A and tacrolimus (FK506), accurate monitoring of NFAT activation in cells, tissues and animals is crucial for biomedical research and drug development.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| TransAM™ NFATc1 | 1 x 96 rxns | 40296 | $ 605 |  |
| TransAM™ NFATc1 | 5 x 96 rxns | 40796 | $ 2595 | |
