		Transcriptional Regulation Co-Immunoprecipitation DNA Repair Luciferase Reporter Assay Nuclear Receptor ELISAs Supershift & Gelshift Assays Transcription Factor ELISA Epigenetics & Chromatin Chromatin Assembly Chromatin IP DNA Damage – Phospho-H2AX DNA Methylation Histone Acetyltransferase Activity (HAT) Histone Deacetylase Activity (HDAC) Histone Purification Methylated Histones Protein Modification GTPase Activation Assay Kinase Assay Substrate Mitosis Assays Nitric Oxide Quantitation Phospho-Protein Detection Sandwich ELISAs SUMOylation Antibodies, Extracts & Proteins Antibodies Cell Extracts Recombinant Proteins Fluorescence & Labeling Albumin Quantification Cell Viability Assay Fluorescent Dyes & Labeling Immunofluorescence Live Cell Membrane Staining Mitosis Determination Protein and Extract Quantification Protein Labeling & Translocation Sample Preparation Fluorescent Dye Labeling Mitochondrial Separation mRNA Isolation Normalization Nuclear & Cytoplasmic Extraction Protein & Extract Quantification Transfection & Expression Competent E. coli Gene Silencing Protein Transfection Staining Reagents Bioinformatics & Text Mining TimeLogic® Biocomputing Solutions AKS 2

TransAM™ p53

The p53 tumor suppressor is a transcription factor that controls the expression of many genes implicated in cell growth control, DNA repair, cell-cycle arrest, apoptosis, angiogenesis, redox regulation, metastasis, nitric oxide production and protein degradation. p53 transactivation is regulated by phosphorylation and interaction with an inhibitory protein, MDM2. Mutational inactivation of the p53 gene product is one of the most common genetic events that occur in human cancers. TransAM p53 contains an antibody specific for the active form of p53 when it is bound to the target DNA.

Name	Format	Cat. No.	Price
TransAM™ p53	1 x 96 rxns	41196	$ 605
TransAM™ p53	5 x 96 rxns	41696	$ 2595

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TransAM™ p53

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