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Sp1 was one of the first cellular transcription factors to be identified, cloned and characterized for its ability to bind to GC-boxes in regulatory promoter elements. Sp1 has always been described as a ubiquitous transcription factor that is required for the constitutive and inducible expression of a variety of genes, such as in the cell cycle and in mammalian development. Identification of new members of the Sp family, e.g. Sp2, Sp3, Sp4 and BTEB have redefined the understanding of Sp1-regulated genes. TransAM Sp1 and Sp1/Sp3 Kits contain antibodies specific for the active form of either Sp1 or Sp1/Sp3 when bound to its target DNA.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| TransAM™ Sp1 | 1 x 96 rxns | 41296 | $ 605 |  |
| TransAM™ Sp1 | 5 x 96 rxns | 41796 | $ 2595 | |
| TransAM™ Sp1/Sp3 | 1 x 96 rxns | 40496 | $ 605 | |
| TransAM™ Sp1/Sp3 | 5 x 96 rxns | 40996 | $ 2595 | |
