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Progesterone is an essential regulator of the reproductive events associated with the establishment and maintenance of pregnancy, including ovulation and uterine & mammary gland development. Progesterone exerts its effects via the intracellular progesterone receptor (PR). PR is composed of two isoforms, A and B. The B form of PR acts as a transcriptional activator in different cellular contexts, whereas the A form functions as a strong inhibitor of transcriptional activity. Quantitative detection of PR levels is very important for predicting prognosis and evaluating the outcome of endocrine therapy in patients with breast and/or uterine cancer.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| NR Sandwich PR | 1 x 96 rxns | 49396 | $ 575 |  |
| NR Sandwich PR | 5 x 96 rxns | 49896 | $ 2450 | |
