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Phosphoinositide 3 Kinase (PI3 Kinase, PI3K) is a regulator of cell proliferation, survival and growth. PI3 Kinase catalyzes the production of phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4,5-biphosphate (PIP2). Growth factors and hormones are responsible for triggering this phosphorylation event and PH domain-containing signaling molecules, including various kinases and their regulators, recognize the resulting product. This activates corresponding cell signaling pathways, eventually leading to cell growth, cell cycle entry, cell migration and cell survival.
| Name | Format | Cat. No. | Price | |
|---|---|---|---|---|
| FACE™ PI3 Kinase p85 | 1 x 96 rxns | 48175 | $ 445 |  |
| FACE™ PI3 Kinase p85 | 5 x 96 rxns | 48675 | $ 1845 | |
| FACE™ PI3 Kinase p85 Chemi | 1 x 96 rxns | 48275 | $ 495 | |
| FACE™ PI3 Kinase p85 Chemi | 5 x 96 rxns | 48775 | $ 2050 | |
