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DNA methylation is a naturally occurring event that affects cell function by altering gene expression. A methyl group is added to the fifth-carbon of cytosine in a CpG dinucleotide by DNA methyltransferase. As aberrant methylation is prevalent in many human cancers, and because methylation is also involved in embryonic development and cell cycle regulation, much research depends on accurately quantifying DNA methylation.
- MethylDetector™ features our optimized bisulfite conversion protocol and a simplified DNA recovery method.
- MethylCollector™ is a unique technology that facilitates methylated DNA recovery from a variety of cell and tissue types.
- Fully Methylated Jurkat DNA is a positive control for assays investigating CpG dinucleotide methylation.
