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Transcriptional Regulation

TransAM™ Nrf2

 

NF-E2-related factor, Nrf2, is a critical transcription factor in oxidative stress signaling. Nrf2 is a basic leucine zipper transcription factor that binds to the antioxidant responsive element (ARE) and may serve as a master regulator in cellular defense pathways in protecting a wide variety of tissues from various toxic exposure.

TransAM™ Nrf2 is a simple solution for studying Nrf2 activation in human, mouse and rat model systems.