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DNA methylation is an epigenetic event that affects cell function by altering gene expression. DNA methylation is involved in embryonic development and cell cycle regulation, while aberrant methylation is prevalent in many human cancers. Active Motif offers a variety of highly characterized antibodies associated with DNA methyltransferases and proteins that recognize and bind methylated DNA.
The antibodies in the table below are directed against proteins involved in DNA methylation and demethylation. Click on antibody name to see its complete information. To find the antibodies you're looking for using a variety of specific search criteria, try our convenient Antibodies Search page.
| Antibody | Applications |
|---|---|
| 5-Hydroxymethylcytidine rabbit polyclonal antibody | DB, IF, IHC, MeDIP |
| 5-Hydroxymethylcytidine rabbit polyclonal antibody (purified IgG) | DB |
| 5-Methylcytidine mouse monoclonal antibody (Clone 33D3) | FACS, IHC, WB, MeDIP |
| CGBP rabbit polyclonal antibody | WB |
| DNMT1 mouse monoclonal antibody | ChIP, IHC, IP, WB |
| DNMT2 rabbit polyclonal antibody | WB |
| DNMT3A mouse monoclonal antibody | ChIP, IF, IHC, WB |
| DNMT3B mouse monoclonal antibody | ChIP, IF, IP, WB |
| Kaiso mouse monoclonal antibody (Clone 6F1D) | WB |
| MBD1 mouse monoclonal antibody | WB |
| MBD1 rabbit polyclonal antibody | WB |
| MBD2 rabbit polyclonal antibody | WB |
| MBD3 mouse monoclonal antibody | WB |
| MBD4 rabbit polyclonal antibody | WB |
| MeCP2 rabbit polyclonal antibody | WB |
| MeCP2 rabbit polyclonal antibody | WB |
| Uhrf1 rabbit polyclonal antibody | WB |
Application Key:
- ChIP = Chromatin Immunoprecipitation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay;
- FACS = Flow Cytometry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methylated DNA Immunoprecipitation;
- WB = Western blot
