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Epigenetics & Chromatin

Sodium phenylbutyrate

Aliases: 4-Phenylbutyric acid sodium salt, 4-PB, PBNa
Catalog No: 14032 Format: 5 g $90 Buy Now
Catalog No: 14033 Format: 1 g $75 Buy Now
Application: Histone Acetylation (HAT & HDAC)

for Sodium phenylbutyrateChemical Properties

MW = 186.2
C10H11O2 Na
CAS 1716-12-7
>98% (TLC; 5% CH3OH in CH2Cl2, Rf = 0.36); NMR (Conforms)

for Sodium phenylbutyrateDescription

Histone deacetylase (HDAC) inhibitor. Inhibits proliferation, migration and invasion of a number of cancer cell lines. Induces differentiation, and apoptosis. Active in vivo.

for Sodium phenylbutyrateContents

White powder. May be dissolved in DMSO (4 mg/ml); Water (25 mg/ml).

for Sodium phenylbutyrateStorage Conditions

Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20°C for up to 3 months.

for Sodium phenylbutyrateReferences

1. HH Engelhard et al. J. Neuro-Oncol. 1998, 37:97
2. IB Appelskog et al. Int. J. Oncol. 2004, 24:1419

 
Chemical structure of Sodium phenylbutyrate.

Chemical structure of Sodium phenylbutyrate.

 

Technical Data Sheet

Sodium phenylbutyrate
 

Data Thumbnails

Chemical structure of Sodium phenylbutyrate.

Chemical structure of Sodium phenylbutyrate.
(Click image to enlarge.)