Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items
Recombinant Proteins & Enzymes

Recombinant PPARα-LBD protein

Aliases: PPAR, NR1C1, hPPAR, PPARalpha
Catalog No: 31141 Format: 10 µg $425 Buy Now
Expressed In: E. coli Protein Species: Human

Request a quote for a bulk orderBulk Order Button


for Recombinant PPARa-LBD proteinContents

10 µg of Recombinant PPARα-LBD protein and Dilution Buffer AM1 (20 mM Tris-Cl (pH 8), 20% glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA). Please refer to product insert upon arrival for lot-specific concentration.

for Recombinant PPARa-LBD proteinBackground

Peroxisome Proliferator-Activated Receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: α, δ and ϒ. PPARs bind to peroxisome proliferator response elements (PPREs) as heterodimers with the retinoid X receptor (RXR).

for Recombinant PPARa-LBD proteinApplication Notes

Recombinant PPARα-LBD protein has been applied in DNA and protein-protein interactions assays, Western blot (32 kDa) and can be used for ligand binding assays (20-100 ng) and protein-protein interactions assays (100 ng). NOTE: The presence of Poly [d(I-C)] in buffers may affect protein functionality and should be avoided.

for Recombinant PPARa-LBD proteinProtein Details

Recombinant PPARα-LBD (accession number NM_005036) is isolated from an E. coli strain that carries the coding sequence of the human PPARα ligand binding domain under the control of a T7 promoter.

for Recombinant PPARa-LBD proteinGuarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

 

Technical Data Sheet

Recombinant PPARα-LBD protein