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Recombinant Proteins & Enzymes

Recombinant PRMT7 protein

Catalog No: 31395 Format: 20 µg $425 Buy Now
Expressed In: Baculovirus Protein Species: Human

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for Recombinant PRMT7 proteinContents

Full length recombinant PRMT7 protein expressed in Sf9 cells and supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 5% Glycerol, 0.04% Triton X-100 and 0.2 mg/ml 3× Flag peptide. Please refer to product insert upon arrival for lot-specific concentration.

for Recombinant PRMT7 proteinBackground

PRMT7 (Protein Arginine Methyltransferase 7) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT7 specifically mediates the symmetrical dimethylation of histone H4 at Arg3 to form H4R3me2s. PRMT7 plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruitment of DNA methyltransferases at these sites. PRMT7 may also play a role in embryonic stem cell (ESC) pluripotency. PRMT7 is also able to mediate arginine methylation of histone H2A and myelin basic protein (MBP) in vitro. However, the biological relevance of such results is unclear.

for Recombinant PRMT7 proteinApplication Notes

Recombinant PRMT7 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.

for Recombinant PRMT7 proteinProtein Details

Recombinant PRMT7 (accession number NP_061896.1) was expressed in Sf9 cells and contains an N-terminal FLAG-Tag with an observed molecular weight of 80.1 kDa. The recombinant protein is >80% pure by SDS-PAGE.

 
PRMT7 Coomassie gel

Recombinant PRMT7 protein gel.
PRMT7 protein was run on a 10% SDS-PAGE gel and stained with Coomassie Blue.

for Recombinant PRMT7 proteinStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant PRMT7 proteinGuarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

 

Technical Data Sheet

Recombinant PRMT7 protein
 

Data Thumbnails

PRMT7 Coomassie gel

PRMT7 Coomassie stained gel.
(Click image to enlarge and see details).