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Recombinant Proteins & Enzymes

Recombinant KAT7 protein

Aliases: Lysine Acetyltransferase 7, HBO1, HBOA, MYST2, Histone Acetyltransferase Binding To ORC1
Catalog No: 31489 Format: 20 µg $395 Buy Now
Expressed In: Baculovirus Protein Species: Human

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for Recombinant KAT7 proteinContents

Full length recombinant KAT7 protein is supplied in 25 mM Hepes pH 7.5, 300 mM NaCl, 5% Glycerol, 0.04% Triton X-100, 0.2 mM TCEP, 0.2 mg/ml 3× Flag peptide. Please refer to product insert upon arrival for lot-specific concentration.

for Recombinant KAT7 proteinBackground

KAT7 (K(Lysine) Acetyltransferase 7) is a MYST-family histone acetyltransferase (HAT) that forms a complex with ING4/5, JADE1/2/3, and Eaf6, which is found enriched on coding regions of genes, supporting a role in transcriptional elongation. In addition, KAT7 is thought to participate in events controlling the initiation of DNA replication.

for Recombinant KAT7 proteinApplication Notes

Recombinant KAT7 protein is suitable for use in enzyme kinetics, inhibitor screening, and selectivity profiling.

for Recombinant KAT7 proteinProtein Details

Full length recombinant KAT7 protein (accession number NP_001186084.1) was expressed in Sf9 cells and contains an N-terminal FLAG-Tag with a molecular weight of 67.2 kDa. The recombinant protein is >85% pure by SDS-PAGE.

 
KAT7 protein Coomassie gel

Recombinant KAT7 protein gel.
Recombinant KAT7 was run on an 8% SDS-PAGE gel and stained with Coomassie blue.

KAT7 protein activity assay

Recombinant KAT7 protein activity assay
Recombinant KAT7 activity titration was assessed using a Radiometry assay. Titration curves were generated to show signal response in the presence of histone peptide substrate at increasing KAT7 concentrations. This data was generated and kindly provided courtesy of ChemPartner.

for Recombinant KAT7 proteinStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant KAT7 proteinGuarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

 

Technical Data Sheet

Recombinant KAT7 protein
 

Data Thumbnails

KAT7 protein Coomassie gel

KAT7 protein Coomassie gel.
(Click image to enlarge and see details).

KAT7 protein activity assay

KAT7 protein activity assay.
(Click image to enlarge and see details).