LAP2 alpha antibody (mAb)

RRID: AB_2793212
Clone: 3A3
Aliases: TMPO, TP, CMD1T, LEMD4, PRO0868
Catalog No: 39267 Format: 200 µl $500 Buy
Catalog No: 39268 Format: 10 µl $125 Buy

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Antibody Type:
Monoclonal
Isotype:
IgG1
Purification:
Ascites
Host:
Mouse
Molecular Weight:
80 kDa
Reactivity:
Human

Applications

Western Blot Validated

Application Notes

Applications Validated by Active Motif:
WB: 1:1,000 - 1:2,000 dilution

Immunogen

This LAP2 alpha antibody was raised against a peptide including the C-terminus of human LAP2 alpha.

Buffer

Ascites containing 30% glycerol and 0.035% sodium azide.

 
LAP2 alpha antibody (mAb) tested by Western blot.

LAP2 alpha mAb (Clone 3A3) tested by Western blot.
Detection of LAP2 alpha by Western blot. The analysis was performed using HeLa nuclear extract and LAP2 alpha mAb (Clone 3A3) at a 1:2,000 dilution.

Background

LAP2 α (Lamin Associated Polypeptide, alpha isoform, Thymopoietin) is a nucleoplasmic protein that oligomerizes and binds Hsp70 and Hsc70. It is involved in the organization of the nuclear structure through its interaction with A-type Lamins (Lamin B1). LAP2 α regulates the cell cycle through its interaction with the Rb protein.

Positive Control

Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for LAP2 alpha antibody (Clone 3A3).

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Guarantee

This product is guaranteed for 12 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • WB = Western Blotting