AML-3/Runx2 antibody (pAb)

for AML-3/Runx2 antibody (pAb)Background

AML-3 (acute myeloid leukemia 3 protein) also known as Runx2 (runt-related transcription factor 2) is a multifunctional transcription factor that can either activate or repress transcription. The alpha subunit can bind DNA as a monomer, or DNA binding can be increased by heterodimerization. AML-3 is necessary for osteoblastic differentiation and skeletal morphogenesis.

for AML-3/Runx2 antibody (pAb)Immunogen

This AML-3/Runx2 antibody was raised against a synthetic peptide corresponding to amino acid residues 333-348 of human AML-3/Runx2.

for AML-3/Runx2 antibody (pAb)Application Notes

This AML-3/Runx2 antibody has been validated for use in electrophoretic mobility shift assays (EMSA). We recommend adding 2 - 6 µl of antibody to the reaction mixture when performing supershift experiments. We also recommend the use of Tris-glycine electrophoresis buffer.

for AML-3/Runx2 antibody (pAb)Buffer

PBS containing 0.2% gelatin, 0.01% thimersol and 0.1% sodium azide.

for AML-3/Runx2 antibody (pAb)Positive Control

Active Motif's Saos-2 nuclear extract (Catalog No. 36025) can be used as a positive control for AML-3/Runx2 antibody.

for AML-3/Runx2 antibody (pAb)Storage

Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for AML-3/Runx2 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.