L3MBTL2 antibody (pAb)

for L3MBTL2 antibody (pAb)Background

L3MBTL2 (Lethal (3) malignant brain tumor-like 2 protein) is a putative member of the polycomb group family and is the human homolog of Drosophila Sfmbt, critical for Hox gene silencing. L3MBTL2 contains one FCS-type zinc finger and four MBT (malignant brain tumor) repeats. L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cells into mitosis. L3MBTL2 is a part of a complex involved in the G₀ phase of the cell cycle. This complex contains other proteins such as E2F-6, Max or HP1 gamma, and participates in transcriptional repression.

for L3MBTL2 antibody (pAb)Immunogen

This L3MBTL2 antibody was raised against a His-tagged fusion protein containing amino acids 1-230 of human L3MBTL2.

for L3MBTL2 antibody (pAb)Application Notes

This L3MBTL2 antibody has been validated for use in Western blotting (1:500 - 1:2,000 dilution) and been reported by a trusted third party to work in chromatin IP (10 µl per ChIP) and immunoprecipitation (5 µl per ChIP).

for L3MBTL2 antibody (pAb)Buffer

Rabbit serum containing 30% glycerol, 0.035% sodium azide.

for L3MBTL2 antibody (pAb)Positive Control

Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for ASH2 pAb.

for L3MBTL2 antibody (pAb)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for L3MBTL2 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.