Histone H3 dimethyl Arg17 asymmetric antibody (pAb)

for Histone H3 dimethyl Arg17 asymmetric antibody (pAb)Background

Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; these modifications play a major role in regulating gene expression. The methylation of histones can occur on two different residues: arginine or lysine.

for Histone H3 dimethyl Arg17 asymmetric antibody (pAb)Immunogen

This antibody was raised against a peptide containing dimethyl-Arg17 (asymmetric) of human histone H3.

for Histone H3 dimethyl Arg17 asymmetric antibody (pAb)Application Notes

This antibody has been validated for use in Western blotting (1:500 - 1:1,000 dilution).

for Histone H3 dimethyl Arg17 asymmetric antibody (pAb)Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide.

for Histone H3 dimethyl Arg17 asymmetric antibody (pAb)Positive Control

Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for Histone H3 dimethyl Arg17 asymmetric pAb.

for Histone H3 dimethyl Arg17 asymmetric antibody (pAb)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Histone H3 dimethyl Arg17 asymmetric antibody (pAb)Guarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.