Ubiquitin antibody (mAb)
|Catalog No: 39741||Format: 100 µg||$385||Buy Now|
|Catalog No: 39742||Format: 10 µg||$85||Buy Now|
for Ubiquitin antibody (mAb) (Clone P4D1)Application Notes
See reference for experimental details. Individual optimization may be required.
for Ubiquitin antibody (mAb) (Clone P4D1)Immunogen
This Ubiquitin antibody was raised against purified bovine ubiquitin.
for Ubiquitin antibody (mAb) (Clone P4D1)Buffer
Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
for Ubiquitin antibody (mAb) (Clone P4D1)References
Click on the Applications below to view references for this antibody:
DOT4 links silencing and cell growth in Saccharomyces cerevisiae. Kahana A. et al. (1999) Mol Cell Biol. 19(10): 6608-20
for Ubiquitin antibody (mAb) (Clone P4D1)Background
Ubiquitin is an important signaling protein that is catalytically added to proteins on lysine residues to modify their function. Addition of multiple ubiquitin proteins in a string (poly-ubiquitylation) to proteins signals their destruction by the proteasome. Mono-ubiquitylation of proteins has a much different effect, more in keeping with post-translational modification of proteins by phosphorylation or acetylation. Mono-ubiquitylation is part of a number of signal transduction pathways, including those involving histone proteins and transcriptional regulation.
for Ubiquitin antibody (mAb) (Clone P4D1)Storage
Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
for Ubiquitin antibody (mAb) (Clone P4D1)Guarantee
This product is guaranteed for 6 months from date of receipt.
This product is for research use only and is not for use in diagnostic procedures.
- ChIP = Chromatin Immunoprecipitation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FACS = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
- WB = Western Blotting