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APOBEC2 antibody (pAb)
| Catalog No: 39985 | Format: 100 µl | $340 | Buy Now |
| Catalog No: 39986 | Format: 10 µl | $70 | Buy Now |
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Applications Table
| Western Blot | Chromatin IP |
|---|---|
| 1:500 - 1:2,000 | — |
for APOBEC2 antibody (pAb)Background
APOBEC2 (Apolipoprotein B mRNA-editing enzyme catalytic subunit 2) is part of a family of enzymes that edit nucleic acids, possibly changing cytosine to uracil. APOBEC2 expression is regulated by TNF-α via NFκB activation and this suggests a possible role for APOBEC2 in the pathophysiology of hepatic inflammation. APOBEC2 has a low intrinsic cytidine deaminase activity and is also involved in DNA demethylation. APOBEC2 deaminates 5-methylcytosine, followed by base excision repair by Mbd4.
for APOBEC2 antibody (pAb)Immunogen
This APOBEC2 antibody was raised against a peptide derived from the N-terminal region of human APOBEC2.
for APOBEC2 antibody (pAb)Application Notes
This APOBEC2 antibody has been validated for use in Western blotting (1:500 - 1:2,000).
for APOBEC2 antibody (pAb)Buffer
Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide.
APOBEC2 antibody (pAb) tested by Western blot.
Nuclear extract (20 µg) of L6E9 cells (Lane 1) or nuclear extract (20 µg) of C2C12 cells (Lane 2) probed with APOBEC2 antibody at a 1:2,000 dilution.
for APOBEC2 antibody (pAb)Storage
Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
for APOBEC2 antibody (pAb)Guarantee
This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.
Application Key
- ChIP = Chromatin Immunoprecipitation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FACS = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- WB = Western Blotting
