Caspase-14 antibody (mAb)

for Caspase-14 antibody (mAb)Background

Caspase-14 (CASP14 or apoptosis-related cysteine peptidase 14) is thought to be a non-apoptotic caspase involved in epidermal differentiation. Caspase-14 has been shown to be processed and activated by Caspase-8 and Caspase 10 in vitro, and also by TNF-Related Apoptosis-Inducing Ligand (TRAIL) in vivo.

for Caspase-14 antibody (mAb)Immunogen

This antibody was raised against a synthetic peptide corresponding to amino acid residues 2-18 of mouse Caspase-14.

for Caspase-14 antibody (mAb)Application Notes

This Caspase-14 antibody has been validated for use in Western blotting (1 - 2 µg/ml dilution). For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required.

for Caspase-14 antibody (mAb)Buffer

PBS containing 0.02% sodium azide. Sodium azide is highly toxic.

for Caspase-14 antibody (mAb)Positive Control

Extracts from mouse spleen can be used as a positive control for Caspase-14 antibody.

for Caspase-14 antibody (mAb)Storage

Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Caspase-14 antibody (mAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.