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Antibodies

TLR6 antibody (mAb)

Clone: 86B1153
Aliases: CD286
Catalog No: 40954 Format: 100 µg $410 Buy Now

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Antibody Type:Monoclonal
Isotype:IgG1
Purification:Affinity Purified
Host:Mouse
Molecular Weight:92 kDa
Reactivity:Human

Applications

Western Blot Validated

for TLR6 antibody (mAb) (Clone 86B1153)Application Notes


Validated Applications:
WB: 2 - 4 µg/ml dilution

For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required.

for TLR6 antibody (mAb) (Clone 86B1153)Immunogen

This TLR6 antibody was raised against a synthetic peptide corresponding to amino acid residues 408-424 of human TLR6.

for TLR6 antibody (mAb) (Clone 86B1153)Buffer

PBS containing 0.02% sodium azide. Sodium azide is highly toxic.

for TLR6 antibody (mAb) (Clone 86B1153)References

 
TLR6 antibody (mAb) tested by Western blot.

TLR6 mAb tested by Western blot.
TLR6 detection by Western blot. The analysis was performed using Daudi whole-cell extract and TLR6 mAb at a 2 µg/ml dilution.

for TLR6 antibody (mAb) (Clone 86B1153)Background

TLR6Toll-Like receptor 6 is a member of the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize specific molecular features associated with pathogens, and mediate the production of cytokines necessary for the development of effective immunity. Many of the TLRs heterodimerize with each other to modulate receptor function. TLR6 forms a heterodimer with TLR2. TLR6 is thought to specify the sensitivity of TLR2 and contribute to its signaling capabilities through heterodimerization.

for TLR6 antibody (mAb) (Clone 86B1153)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for TLR6 antibody (mAb) (Clone 86B1153)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

TLR6 antibody (mAb)
 

Data Thumbnails

TLR6 antibody (mAb) tested by Western blot.

Western blot of TLR6 mAb.
(Click image to enlarge and see details.)