p73 antibody (mAb)

for p73 antibody (mAb)Background

p73 is a p53-related tumor protein, with some structural resemblance to p53, and is therefore considered a tumor-suppressor protein. p73 has numerous isoforms arising from alternative splicing, resulting in 6 different C-termini. Overexpression of p73 promotes growth arrest and/or apoptosis in a manner similar to that seen with p53.

for p73 antibody (mAb)Immunogen

This antibody was raised against a full-length protein corresponding to human p73.

for p73 antibody (mAb)Application Notes

This p73 antibody has been validated for use in Western blotting (1:500 dilution). For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. This p73 antibody reacts with an epitope that is located on the N-terminal region of human p73 and does not cross react with p53. The p73 protein may run at 63 kDa in some cell lines due to post-transcriptional modifications.

for p73 antibody (mAb)Buffer

PBS containing 0.02% sodium azide. Sodium azide is highly toxic.

for p73 antibody (mAb)Positive Control

Extracts from cells transfected with p73 can be used as a positive control for p73 antibody.

for p73 antibody (mAb)Storage

Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for p73 antibody (mAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.