p63 antibody (mAb)

for p63 antibody (mAb)Background

p63, also known as TP63 (for tumor protein p63), is a p53-related tumor protein with some structural resemblance to p53, and is therefore considered a tumor-suppressor protein. p63 has numerous isoforms arising from alternative splicing, resulting in 6 different C-termini. Overexpression of p63 promotes growth arrest and/or apoptosis in a manner similar to that seen with p53. It is associated with ectrodactyly-ectodermal dysplasia-cleft syndrome and Hay-Wells syndrome.

for p63 antibody (mAb)Immunogen

This p63 antibody was raised against a synthetic peptide corresponding to human p63.

for p63 antibody (mAb)Application Notes

This p63 antibody has been validated for use in Western blotting (3 - 5 µg/ml dilution). For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required.

for p63 antibody (mAb)Buffer

PBS containing 0.02% sodium azide. Sodium azide is highly toxic.

for p63 antibody (mAb)Positive Control

Whole-cell extracts from 293 cells can be used as a positive control for p63 antibody.

for p63 antibody (mAb)Storage

Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for p63 antibody (mAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.