MED1 antibody (pAb)

for MED1 antibody (pAb)Background

MED1 (Mediator complex subunit 1, TRIP2, Thyroid receptor-interacting protein 2) is a component of the Mediator complex, a coactivator involved in the regulated transcription of most genes transcribed by RNA polymerase II. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. MED1 is involved in supporting hematopoietic stem and/or progenitor cell function.

for MED1 antibody (pAb)Immunogen

This MED1 antibody was raised against a peptide within the C-terminal region of human MED1.

for MED1 antibody (pAb)Application Notes

This MED1 (TRIP2) antibody has been validated for use in Western blotting (1:500 - 2,000).

for MED1 antibody (pAb)Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide.

for MED1 antibody (pAb)Positive Control

Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for MED1 (TRIP2) antibody.

for MED1 antibody (pAb)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for MED1 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of arrival.