Histone H1 antibody (pAb)

for Histone H1 antibody (pAb)Background

The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points. Histone H1 is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation and play a major role in regulating gene expression.

for Histone H1 antibody (pAb)Immunogen

This Histone H1antibody was raised against purified calf thymus Histone H1.

for Histone H1 antibody (pAb)Application Notes

This Histone H1 antibody has been validated for use in Western blotting (0.5 - 2 µg/ml).

for Histone H1 antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.

for Histone H1 antibody (pAb)Positive Control

Active Motif's HeLa acid extract (Catalog No. 36200) can be used as a positive control for Histone H1 antibody.

for Histone H1 antibody (pAb)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Histone H1 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of arrival.