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EED antibody (mAb)
| Clone: 41D |
| Catalog No: 61203 | Format: 100 µg | $340 | Buy Now |
| Catalog No: 61204 | Format: 10 µg | $70 | Buy Now |
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Applications Table
| Western Blot | Chromatin IP |
|---|---|
| Yes | — |
for EED antibody (mAb) (Clone 41D)Background
EED (extraembryonic ectoderm) is a component of the Polycomb group (PcG) multiprotein complex PRC2. The PRC2 complex also contains EZH2 and SUZ12 and is recruited to Polycomb response elements and results in the methylation of histone H3 and lysine 27 and the silencing of gene expression. PRC2 initiates repression of the Hox genes during development and is involved in the maintenance of stem cell pluripotency. EED is a member of the superfamily of WD-40 repeat protein family and is required for PRC2-mediated H3K27 methylation. The PRC2 complex may also recruit platform DNMTs, thereby linking two systems of epigenetic repression.
for EED antibody (mAb) (Clone 41D)Immunogen
This EED antibody was raised against full-length recombinant human EED protein.
for EED antibody (mAb) (Clone 41D)Application Notes
This antibody has been validated for use in Immunohistochemistry (2 - 8 µg/ml and has been reported to work in Western blotting.
for EED antibody (mAb) (Clone 41D)Buffer
Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
EED mAb tested by Immunohistochemistry .
EED detection by Immunohistochemistry. The analysis was performed using human tonsil paraffin section and the EED mAb.
for EED antibody (mAb) (Clone 41D)Storage
Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
for EED antibody (mAb) (Clone 41D)Guarantee
This product is guaranteed for 6 months from date of arrival.
Application Key
- ChIP = Chromatin Immunoprecipitation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FACS = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- WB = Western Blotting
