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Antibodies

KDM4C antibody (pAb)

Aliases: GASC1, JHDM3C, JMJD2C, TDRD14C
Catalog No: 61687 Format: 100 µl $410 Buy Now
Catalog No: 61688 Format: 10 µl $95 Buy Now

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Antibody Type:Polyclonal
Isotype:IgG
Purification:Affinity Purified
Host:Rabbit
Molecular Weight:142 kDa
Reactivity:Monkey

Applications

Western Blot Validated

for KDM4C antibody (pAb)Application Notes


Validated Applications:
WB: 1:500 dilution

for KDM4C antibody (pAb)Immunogen

This antibody was raised against a peptide within human KDM4C.

for KDM4C antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for KDM4C antibody (pAb)References

 
KDM4C antibody (pAb) tested by Western blot.

KDM4C antibody (pAb) tested by Western blot.
COS-7 nuclear extract (25 µg per lane) was probed with KDM4C pAb at a 1:500 dilution.
Lane 1: No treatment.
Lane 2: Cells treated with CoCl2.

for KDM4C antibody (pAb)Background

KDM4C (Lysine (K)-Specific Demethylase 4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

for KDM4C antibody (pAb)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for KDM4C antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

KDM4C antibody (pAb)
 

Data Thumbnails

KDM4C antibody (pAb) tested by Western blot.

Western blot of KDM4C pAb.
(Click image to enlarge and see details.)