Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items
    
Recombinant Proteins & Enzymes

Recombinant SSRP1 / FACT p80 protein

Catalog No: 81094 Format: 20 µg $405 Buy Now
Catalog No: 81894 Format: 1 mg $3,500 Buy Now
Expressed In: Baculovirus Protein Species: Human

Request a quote for a bulk orderBulk Order Button


for Recombinant SSRP1 / FACT p80 proteinContents

Recombinant SSRP1 / FACT p80 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100 and 0.5 mM TCEP.

for Recombinant SSRP1 / FACT p80 proteinBackground

SSRP1 (Structure Specific Recognition Protein 1), also known as FACT p80 (Facilitates Chromatin Transcription Complex 80 KDa Subunit), is a component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of Ser-392 of p53/TP53 via its association with CK2 (casein kinase II). 

for Recombinant SSRP1 / FACT p80 proteinApplication Notes

This protein is suitable for use in protein-protein interaction, in vitro transcription assay, binding assay.

for Recombinant SSRP1 / FACT p80 proteinProtein Details

Recombinant human SSRP1 / FACT p80 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003137.1) with an N-terminal FLAG tag. The molecular weight of the protein is 82.2 kDa.

 
Recombinant SSRP1 / FACT p80 protein gel

Recombinant SSRP1 / FACT p80 protein gel
7.5% SDS-PAGE Coomassie staining
MW: 82.2 kDa
Purity: >95%

for Recombinant SSRP1 / FACT p80 proteinStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant SSRP1 / FACT p80 proteinGuarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.

 

Technical Data Sheet

Recombinant SSRP1 / FACT p80 protein
 

Data Thumbnails

Recombinant SSRP1 / FACT p80 protein gel

Recombinant SSRP1 / FACT p80 protein gel
(Click to enlarge and view details)