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Recombinant Proteins & Enzymes

Recombinant BRDT (21-137) protein, GST-Tag

Catalog No: 81156 Format: 100 µg $395 Buy Now
Catalog No: 81856 Format: 1 mg $2,600 Buy Now
Expressed In: E. coli Protein Species: Human

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for Recombinant BRDT (21-137) protein, GST-TagContents

Recombinant BRDT (21-137) protein, GST-Tag is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10% glycerol.

for Recombinant BRDT (21-137) protein, GST-TagBackground

BRDT is similar to the RING3 protein family. It possesses two bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain functions as a ‘reader’ of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. It shows binding specificity for acetylated H2BK12/15, H3K9/14/18/23, H4K12, H4K5/8, H4K8/12, H4K12/16, H4K5/12, H4K5/8/12/16 and H4K5/8/12/16.

for Recombinant BRDT (21-137) protein, GST-TagApplication Notes

This protein is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

for Recombinant BRDT (21-137) protein, GST-TagProtein Details

Recombinant BRDT (21-137) protein, GST-Tag that includes amino acids 21-137 (Bromo domain) of human BRDT protein (accession number NP_001229735.2) was expressed in E.coli and contains an N-terminal GST Tag with a molecular weight of 40.2 kDa.

for Recombinant BRDT (21-137) protein, GST-TagStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant BRDT (21-137) protein, GST-TagGuarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.

 

Technical Data Sheet

Recombinant BRDT (21-137) protein, GST-Tag