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Recombinant Proteins & Enzymes

Recombinant NSUN2 protein

Catalog No: 81171 Format: 20 µg $405 Buy Now
Catalog No: 81871 Format: 1 mg $3,500 Buy Now
Expressed In: Baculovirus Protein Species: Human

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for Recombinant NSUN2 proteinContents

Recombinant NSUN2 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100, 0.5 mM TCEP.

for Recombinant NSUN2 proteinBackground

NSUN2 (NOP2/Sun Domain Family, Member 2), also called as TRM4 (TRNA Methyltransferase 4 Homolog), is a member of NSUN family. It’s a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 also methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of introncontaining tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. NSUN2 is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

for Recombinant NSUN2 proteinApplication Notes

Recombinant NSUN2 protein is suitable for use in enzyme kinetics, inhibitor screening, and selectivity profiling.

for Recombinant NSUN2 proteinProtein Details

Recombinant NSUN2 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_060225.4) with an N-terminal FLAG tag. The molecular weight of the protein is 88.1 kDa.

 
Recombinant NSUN2 protein

Recombinant NSUN2 protein
10% SDS-PAGE Coomassie staining
MW: 88.1 kDa
Purity: >80%

for Recombinant NSUN2 proteinStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant NSUN2 proteinGuarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.

 

Technical Data Sheet

Recombinant NSUN2 protein
 

Data Thumbnails

Recombinant NSUN2 protein

Recombinant NSUN2 protein
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