ChIP-Validated Antibodies

antibodies verified to function in chromatin immunoprecipitation

Chromatin immunoprecipitation (chromatin IP or ChIP) is an extremely challenging technique, and only antibodies of the highest quality will do. For an antibody to work in chromatin IP, it must be of high titer and it must be very specific, with no detection of non-target proteins. Most importantly, it must be able to recognize the target protein in its native chromatin-associated context after fixation. Active Motif specializes in manufacturing high-quality antibodies to histones, histone modifications and chromatin proteins and validating them for use in ChIP, as well as ChIP-Seq & ChIP-chip. In addition, our Epigenetic Services team offers ChIP Antibody Validation Services in which we will determine if your antibody is suitable for use in ChIP, ChIP-Seq or ChIP-chip.

To help make your ChIP even more successful, Active Motif offers its complete line of ChIP-IT® Express Kits for performing Chromatin IP, high-throughput ChIP, sequential ChIP and even RNA ChIP.

The antibodies in the table below have been validated for use in ChIP. Click on antibody name to see its complete information. To find specific antibodies, use the Search box at the top of the page, or you can choose to see antibodies by various groups by selecting from the lists under Available Products on the right side of the page.

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Product Category Primary Antibodies (264) Bridging Antibody (1)
Antibody Type Polyclonal (152) Monoclonal (90) Recombinant (23)
Host Rabbit (155) Mouse (92) Rat (17)
Isotype IgG (103) Serum (64) IgG2a (42) IgG1 (30) IgG2b (13) IgG1, k (8) IgG3 (3) IgG2a, k (1) IgG2c (1)
Reactivity Human (245) Wide Range Predicted (124) Mouse (98) Budding Yeast (18) Rat (13) Not Species Specific (8) Drosophila (5) Fission Yeast (5) Hamster (2) Monkey (2) C. elegans (1)
Modification None (136) Methylated (51) Acetylated (49) Phosphorylated (14) AM-Tag (1) Ubiquitinated (1)
Purification None (66) Protein G Chromatography (64) Protein A Chromatography (63) Affinity Purified (57) Ni-NTA (10) Culture Supernatant (3) Ascites (2)
Antibody Category Histones (126) Transcriptional Regulation (116) Stem Cells (89) Chromatin Modifiers (58) AbFlex Recombinant Antibodies (19) Cell Biology (10) DNA Methylation (10) DNA Damage (8) Nuclear Receptors (6) Cell Signaling & Signal Transduction (4) Apoptosis (3) RNA Processing (2) Cell Cycle (1) Epitope Tag (1)
Histone Products Histone H3 (77) Histone H4 (24) Histone H2A (11) Histone H2B (7) Histone H2AZ (3) Histone H2Av (2) Histone H1 (1) Histone H2AX (1)
Name Isotype Reactivity Appl. Format Cat No. Price  
5-Methylcytosine (5-mC) antibody (mAb) IgG Human, Not Species Specific ELISA, IHC, MeDIP 50 µg 39649 $240 Buy
5-Methylcytosine (5-mC) antibody (pAb) IgG Human, Not Species Specific ChIP, DB, IHC, MeDIP 100 µg 61255 Discontinued
10 µg 61256 Discontinued
50 µg 61955 Discontinued
Ago1/2/3 antibody (mAb) IgG Human ChIP, ICC, IF, IHC, IP, WB 100 µg 39937 $470 Buy
10 µg 39938 $115 Buy
Ago3 antibody (mAb) IgG2a Human ChIP, ICC, IF, IP 100 µg 39787 $470 Buy
10 µg 39788 $115 Buy
AIB1 / SRC-3 antibody (pAb) IgG Human ChIP, WB 100 µl 39797 $470 Buy
10 µl 39798 $115 Buy
AID antibody (mAb) IgG2a Human, Mouse ChIP, WB 100 µg 39885 $470 Buy
10 µg 39886 $115 Buy
AbFlex® AM-Tag antibody (rAb) IgG2a Human, Not Species Specific ChIP, ELISA, WB 100 µg 91111 $350 Buy
10 µg 91112 $75 Buy
AbFlex® AM-Tag antibody (rAb) (biotin) IgG2a Human, Not Species Specific ChIP, ELISA, WB 100 µg 91109 Discontinued
10 µg 91110 Discontinued
AM-Tag antibody (pAb) IgG Human, Not Species Specific ChIP, WB 100 µg 61677 Discontinued
10 µg 61678 Discontinued
AML-1/Runx1 antibody (pAb) IgG Human, Mouse ChIP, ICC, IF, IHC, IP, WB 100 µl 39000 Discontinued