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Because histone proteins are crucial to the organization of genomic DNA, post-translational modifications of histones are important regulators of genome function. Histone modifications are involved in the regulation of transcription and play a role in maintaining discrete regions of active and inactive chromatin. Active Motif is developing a panel of antibodies for all widely studied and biologically relevant modification sites. All of our antibodies are rigorously screened for specificity and tested to verify which applications they work well in,
Click the links below for a list of antibody products related to each histone:
Histone H1 • Histone H2A • Histone H2B • Histone H3 • Histone H4
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Antibody Category = Histones
| Antibody Type | Polyclonal (148) Monoclonal (54) Recombinant (34) |
|---|---|
| Application | Western blot (230) Chromatin Immunoprecipitation (126) Dot Blot (123) Immunofluorescence (105) Immunocytochemistry (83) ChIP-Seq (72) CUT&Tag (24) Dot blot (15) Immunohistochemistry (13) ELISA (10) Immunoprecipitation (8) CUT&RUN (6) |
| Host | Rabbit (159) Mouse (66) Rat (11) |
| Isotype | IgG (97) Serum (64) IgG2a (39) IgG1 (21) IgG2b (10) IgG1, k (4) IgG3 (1) |
| Reactivity | Human (216) Wide Range Predicted (191) Mouse (37) Budding Yeast (19) Fission Yeast (8) Drosophila (5) Not Species Specific (2) Rat (2) Canine (1) |
| Modification | Methylated (81) Acetylated (60) None (55) Phosphorylated (28) Biotinylated (2) Ubiquitinated (2) AM-Tag (1) Propionylated (1) |
| Purification | Protein A Chromatography (79) None (70) Affinity Purified (42) Protein G Chromatography (36) Ni-NTA (4) Ascites (3) Culture Supernatant (2) |
| Histone Products | Histone H3 (133) Histone H4 (36) Histone H2A (32) Histone H2B (14) Histone H2AZ (6) Histone H1 (5) Histone H2AX (4) Histone H2Av (2) |
| Name | Isotype | Reactivity | Appl. | Format | Cat No. | Price | |
|---|---|---|---|---|---|---|---|
| Acetyl-Lysine antibody (rAb) | IgG | Human, Not Species Specific | ICC, WB | 100 µg | 91315 | $500 | Buy |
| AbFlex® AM-Tag antibody (rAb) | IgG2a | Not Species Specific | ChIP, ELISA, WB | 100 µg | 91111 | $385 | Buy |
| 10 µg | 91112 | $85 | Buy | ||||
| BRD3 antibody (pAb) | IgG | Human, Mouse | ChIP, ChIP-Seq, CUT&RUN, WB | 100 µl | 61489 | $510 | Buy |
| 10 µl | 61490 | $125 | Buy | ||||
| AbFlex® EHMT2 (G9a) antibody (rAb) | IgG2a | Human | WB | 100 µg | 91229 | $385 | Buy |
| 10 µg | 91230 | $85 | Buy | ||||
| Histone H1 antibody (mAb) | IgG1 | Drosophila | ChIP, ChIP-Seq, IF, IP, WB | 100 µg | 61785 | $510 | Buy |
| 10 µg | 61786 | $125 | Buy | ||||
| Histone H1 antibody (pAb) | Serum | Human, Wide Range Predicted | ICC, IF, WB | 100 µl | 39707 | $500 | Buy |
| 10 µl | 39708 | $125 | Buy | ||||
| Histone H1 antibody (pAb) | IgG | Human, Wide Range Predicted | WB | 100 µg | 61201 | $500 | Buy |
| 10 µg | 61202 | $125 | Buy | ||||
| Histone H1.0 antibody (pAb) | IgG | Human, Mouse | WB | 100 µl | 61417 | $500 | Buy |
| 10 µl | 61418 | $125 | Buy | ||||
| Histone H1.5S17ph antibody (pAb) | IgG | Human, Wide Range Predicted | DB, WB | 100 µl | 61107 | $500 | Buy |
| 10 µl | 61108 | $125 | Buy | ||||
| Histone H2A antibody (pAb) | IgG | Human | WB | 100 µg | 39209 | $500 | Buy |
