Bcl10 antibody (mAb)
|Aliases: CLAP, mE10, CIPER, c-E10, CARMEN|
|Catalog No: 39393||Format: 200 µg||$295||Buy|
|Catalog No: 39394||Format: 10 µg||$95||Buy|
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Applications Validated by Active Motif:
IP: 10 µg per IP
WB: 0.5 - 2 µg/ml dilution
This Bcl10 antibody was raised against full-length recombinant human Bcl10 protein.
Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Bcl10 (B-cell CLL/lymphoma 10) protein promotes apoptosis and activation of NFκB (NFκB p50 & NFκB p65) via NIK and IKK (IKKα, IKKβ, IKKi/IKKε and IKKγ). Bcl10 protein contains a caspase recruitment domain (CARD) which interacts with other CARD domain containing proteins to regulate NFκB signaling. It is also a substrate for MALT1.
Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for Bcl10 antibody (Clone 151).
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
This product is guaranteed for 12 months from date of receipt.
This product is for research use only and is not for use in diagnostic procedures.
- ChIP = Chromatin Immunoprecipitation;
- ChIP = ChIP Sequencing;
- CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
- CUT&Tag = Cleavage Under Targets and Tagmentation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FC = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- NEU = Neutralizing;
- WB = Western Blotting