MALT1 antibody (mAb)

Aliases: MLT, MLT1, IMD12
Catalog No: 39395 Format: 200 µg $435 Buy
Catalog No: 39396 Format: 10 µg $105 Buy

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Antibody Type:
Protein G Chromatography
Molecular Weight:
92 kDa


Western Blot Validated

Application Notes

Validated Applications:
WB: 0.5 - 2 µg/ml dilution


This MALT1 antibody was raised against a recombinant protein corresponding to amino acids 701-808 of mouse MALT1.


Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.


MALT1 antibody (mAb) tested by Western blot.

MALT1 mAb tested by Western blot.
MALT1 detection by Western blot. The analysis was performed using 20 µg Jurkat nuclear extract and MALT1 mAb at a 2 µg/ml dilution.


MALT1 enhances Bcl10-induced activation of NFκB and is also involved in nuclear export of Bcl10. MALT1 binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. MALT1 dependent Bcl10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. MALT1 was independently identified as a protein of 824 amino acids, and human MALT2 isoform b is an amino acid protein of 813 amino acids. MALT1 is thought to play a role in NFκB signaling by enhancing NFκB (NFκB p50 and NFκB p65) activation through interaction with Bcl10. Interaction between MALT1 and Bcl10 mediates IKK (IKKα, IKKβ Clone 10AG2, IKKβ Clone 10A9B6, IKKi/IKKε and IKKγ) activation in vitro through facilitating the ubiquitination of NEMO by the ubiquitin conjugating enzyme UBC13.

Positive Control

Active Motif's Jurkat nuclear extract (Catalog No. 36014) can be used as a positive control for MALT1 antibody.


Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.


This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting