Caspase-7 antibody (mAb)

for Caspase-7 antibody (mAb) (Clone 25B204.1)Application Notes

Validated Applications:
WB: 1 - 2 µg/ml dilution

For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required.

for Caspase-7 antibody (mAb) (Clone 25B204.1)Immunogen

This Caspase-7 antibody was raised against a recombinant human Caspase-7 protein.

for Caspase-7 antibody (mAb) (Clone 25B204.1)Buffer

PBS containing 0.02% sodium azide. Sodium azide is highly toxic.

for Caspase-7 antibody (mAb) (Clone 25B204.1)References

for Caspase-7 antibody (mAb) (Clone 25B204.1)Background

Caspase-7 (CASP7 or apoptosis-related cysteine peptidase 7) is involved in the activation cascade of caspases responsible for apoptosis execution. The precursor form of Caspase-7 is cleaved by Caspase-3 and Caspase-10, which is activated by cell death stimuli and induces apoptosis. Caspase-7 cleaves and activates sterol regulatory element binding proteins (SREBPs) and proteolytically cleaves poly(ADP-ribose) polymerase (PARP, see PARP-1 C-terminal and PARP-1 N-terminal antibodies).

for Caspase-7 antibody (mAb) (Clone 25B204.1)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for Caspase-7 antibody (mAb) (Clone 25B204.1)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.