RXR-β antibody (mAb)

Clone: 16RX-2E1
Aliases: Rxrb, Rub, Nr2b2, RCoR-1, AL023085, H-2RIIBP
Catalog No: 61031 Format: 100 µg $435 Buy

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Antibody Type:
Monoclonal
Isotype:
IgG1
Purification:
Protein G Chromatography
Host:
Mouse
Molecular Weight:
56 kDa
Reactivity:
Human

Applications

Western Blot Validated Immunohistochemistry Validated

Application Notes


Published Applications:
IHC
WB
See references for more information. Individual optimization may be required.

Immunogen

This RXR-beta antibody was raised against a peptide within the N-terminal A region of mouse RXR-beta.

Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

References

Background

RXR-β (retinoid X receptor beta, NR2B2) is a member of the nuclear receptors superfamily, specifically those involved in mediating the effects of retinoic acid (RA). RXR-β forms heterodimers with the RAR (retinoic acid receptor), TR (thyroid hormone receptor) and the VDR (vitamin D receptor), increasing both DNA binding and transcriptional function on their respective response elements.

Positive Control

Active Motif's Recombinant RXR-β protein (Catalog No. 31134) can be used as a positive control for RXR-β antibody.

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting