Rad21 antibody (mAb)

for Rad21 antibody (mAb) (Clone 52A311)Background

Rad21 Clone 52A311 (HR21, MCD1, NXP1, hHR21) is highly similar to the gene product of S. pombe Rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. Rad21 is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of Rad21 with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

for Rad21 antibody (mAb) (Clone 52A311)Immunogen

Recombinant protein corresponding to the N-terminal half of mouse Rad21.

for Rad21 antibody (mAb) (Clone 52A311)Application Notes

This Rad21 antibody (Clone 52A311) has been validated for use in Western blotting (0.5 - 2 µg/ml dilution).

for Rad21 antibody (mAb) (Clone 52A311)Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide.

for Rad21 antibody (mAb) (Clone 52A311)Positive Control

Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for Rad21 antibody (Clone 52A311).

for Rad21 antibody (mAb) (Clone 52A311)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Rad21 antibody (mAb) (Clone 52A311)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.