Active Motif,
Tools to analyze nuclear function,
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Sample Preparation

Sonication Products

reproducible sonication for more consistent results

Active Motif’s EpiShear™ sonication products are ideal for shearing chromatin and DNA for use in chromatin immunoprecipitation (ChIP), DNA methylation studies and Next-Gen sequencing. They were designed to save you time and effort, and include features like fully programmable digital generators that give you the control needed to get the most reproducible results possible.

The EpiShear Multi-Sample Sonicator is a cup horn sonicator that can shear 1-8 samples simultaneously. Its compact design merges all components into a very small footprint. So, it will fit (and not be too noisy to use) anywhere in your lab. It includes a digitally programmable generator, a sound enclosure housing the sonicator / water bath, and can be supplied with or without our thermoelectric chiller.

EpiShear Multi-Sample Sonicator
EpiShear™ Multi-Sample Sonicator.

The EpiShear Probe Sonicator offers you the flexibility to shear both small or large sample sizes. With the supplied 1/8" microtip probe, you can process samples from 500 µl to 15 ml. Other probes are available, which increase the range of samples that can be processed to 200 µl up to 50 ml.

The EpiShear Cooled Sonication Platform enables you to precisely position the depth of any probe in your sample every time, helping ensure consistent results from sample to sample. Tube coolers that hold microfuge, 15 ml and 50 ml tubes keep your samples cold during sonication, so you'll never again waste your time moving your samples to and from an ice bucket to protect them from heat build up.

EpiShear Probe Sonicator and the Cooled Sonication Platform
EpiShear™ Probe Sonicator and
Cooled Sonication Platform.

A variety of accessories are available for use with the EpiShear Probe Sonicator, including different sizes of microtip probes, a sound enclosure to reduce noise, a converter stand for hands-free use, and a footswitch that makes it more convenient to deliver short pulses when using the unit in manual mode.

Probe Sonicator
Sound Enclosure.