Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items


Sign up to receive new product updates
and promotional pricing.

Sample Preparation

Sonication Products

reproducible sonication for more consistent results

Active Motif’s EpiShear™ sonication products are ideal for shearing chromatin and DNA for use in chromatin immunoprecipitation (ChIP), DNA methylation studies and Next-Gen sequencing. They were designed to save you time and effort, and include features like fully programmable digital generators that give you the control needed to get the most reproducible results possible.

The EpiShear Probe Sonicator offers you the flexibility to shear both small or large sample sizes. With the supplied 1/8" microtip probe, you can process samples from 500 µl to 15 ml. Other probes are available, which increase the range of samples that can be processed to 200 µl up to 50 ml.

A variety of accessories are available for use with the EpiShear Probe Sonicator, including different sizes of microtip probes, a sound enclosure to reduce noise, a converter stand for hands-free use, and a footswitch that makes it more convenient to deliver short pulses when using the unit in manual mode. More >

EpiShear Probe Sonicator and the Cooled Sonication Platform
EpiShear™ Probe Sonicator with
support stand / converter clamp.

Sonicator Pricing Information

The The EpiShear™ Cooled Sonication Platform greatly increases sample-to-sample reproducibility when shearing chromatin or DNA by enabling you to precisely position the sonicator probe at the exact same depth, in each sample, every time. Tube coolers that hold microfuge, 15 ml, and 50 ml tubes keep your samples cold during sonication, so you'll never again waste your time moving your samples to and from an ice bucket to protect them from heat build up. Each unit is also supplied in a sound enclosure to help reduce the noise of sonication. More >

EpiShear Probe Sonicator and the Cooled Sonication Platform
EpiShear™ Cooled Sonication Platform and sound enclosure.

Sonicator Cooled Platform Pricing Information