MTA2 antibody (pAb)

for MTA2 antibody (pAb)Background

MTA2 (Metastasis-associated protein 2) is a member of the Mi-2/NuRD complex, a nucleosome (chromatin) remodeling deacetylase complex. The MTA family sequences contain several common domains, potentially involved in protein-protein interactions (BAH domain), in DNA binding (SANT domain and GATA-type zinc finger motif) and in signal transduction involving many kinase, adaptor and scaffolding proteins (src-homology (SH)-binding motifs). Tumor suppressor p53 protein is deacetylated by both MTA1 and MTA2, leading to inhibition of growth arrest in transforming cells supporting a link between these protein family members and metastasis. MTA2 is ubiquitously expressed.

for MTA2 antibody (pAb)Immunogen

This MTA2 antibody was raised against a peptide corresponding to the C-terminus of human MTA2.

for MTA2 antibody (pAb)Application Notes

This MTA2 antibody has been validated for use in Western blotting (1:500 - 1:2,000 dilution).

for MTA2 antibody (pAb)Buffer

Rabbit serum containing 30% glycerol and 0.035% sodium azide.

for MTA2 antibody (pAb)Positive Control

Active Motif's 293 nuclear extract (Catalog No. 36033) can be used as a positive control for MTA2 antibody.

for MTA2 antibody (pAb)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for MTA2 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.