Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items
    
Recombinant Proteins & Enzymes

Recombinant ALKBH4 protein

Catalog No: 81131 Format: 100 µg $395 Buy Now
Catalog No: 81831 Format: 1 mg $2,600 Buy Now
Expressed In: E. coli Protein Species: Human

Request a quote for a bulk orderBulk Order Button


for Recombinant ALKBH4 proteinContents

Recombinant ALKBH4 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10% glycerol, and 0.5 mM TCEP

for Recombinant ALKBH4 proteinBackground

ALKBH4 (Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 4) is a member of ALKBH protein family. It’s a dioxygenase that mediates demethylation of actin monomethylated at Lys-84 (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. ALKBH4 may also be involved in transcription regulation.

for Recombinant ALKBH4 proteinApplication Notes

Recombinant ALKBH4 protein is suitable for use in enzyme kinetics, inhibitor screening, and selectivity profiling.

for Recombinant ALKBH4 proteinProtein Details

Full length ALKBH4 protein (accession number NP_060091.1) was expressed in E.coli cells with an N-terminal 6Å~His tag. The molecular weight of ALKBH4 is 37.4 kDa.

 
Recombinant ALKBH4 protein gel

Recombinant ALKBH4 protein gel
12.5% SDS-PAGE Coomassie staining
MW: 37.4 kDa
Purity: >85%

for Recombinant ALKBH4 proteinStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant ALKBH4 proteinGuarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.

 

Technical Data Sheet

Recombinant ALKBH4 protein
 

Data Thumbnails

Recombinant ALKBH4 protein gel

Recombinant ALKBH4 protein gel
(Click to enlarge and view details)