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Recombinant Proteins & Enzymes

Recombinant Histone H3/H4 tetramer

Catalog No: 81169 Format: 100 µg $405 Buy Now
Catalog No: 81869 Format: 1 mg $3,200 Buy Now
Expressed In: E. coli Protein Species: Human

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for Recombinant Histone H3/H4 tetramerContents

Recombinant Histone H3/H4 Tetramer is in 10 mM Tris-HCl pH 7.4, 2 M NaCl, 1 mM EDTA, 10% glycerol, and 5 mM b-mercaptoethanol.

for Recombinant Histone H3/H4 tetramerBackground

Histone H3 and H4 are the core components of the nucleosome. H3 and H4 assemble H3/H4 tetramer, and H3/K4 tetramer combines with two H2A/H2B dimers to form histone octamer. The histone octamer is wrapped around by 146 bp DNA to assemble a nucleosome, which is the basic structural unit of chromatin in vivo.

for Recombinant Histone H3/H4 tetramerApplication Notes

Recombinant Histone H3/H4 Tetramer is suitable for use as substrates in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.

for Recombinant Histone H3/H4 tetramerProtein Details

Recombinant histone H3/K4 Tetramer consists of full length human histones H3 (accession number NP_003520.1) and full length human histone H4 (accession number NP_003539.1). Histone H3 and H4 were expressed in E. coli cells. Recombinant histone H3/H4 Tetramer was assembled by dialysis and purified by gel filtration. The molecular weight of the Histone H3/H4 Tetramer is 53 kDa.

 
Recombinant Histone H3/H4 Tetramer

Recombinant Histone H3/H4 Tetramer
13% SDS-PAGE Coomassie staining

MW:
H3: 15.3 kDa
H4: 11.2 kDa

Purity: ≥ 90%

for Recombinant Histone H3/H4 tetramerStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant Histone H3/H4 tetramerGuarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.

 

Technical Data Sheet

Recombinant Histone H3/H4 tetramer
 

Data Thumbnails

Recombinant Histone H3/H4 Tetramer

Recombinant Histone H3/H4 Tetramer
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